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PHARMACEUTICAL AND ANALYTICAL STUDY OF HERBAL DEODORANT“SEVYA” AEROSOL FORMULATION BY USING AYURVEDIC DRUGS ANDEVALUTATION OF ITS ANTI-MICROBIAL ACTIVITY

Priyanka Gomase, Dr. Prashant Bedarkar, Prof. B.J. Patgiri

Vol. 8, Issue 1, Jul-Dec 2019

Abstract:

Introduction: Ushira (Rhizomes of Vetiveria zizanioides), sariva (Rhizomes of Hemidesmusindicus) and Bilva patra (leaves of Aegle marmelos) are commonly used, found, aromatic drugs withwide spectrum therapeutic utility especially for skin disorders. Their alcoholic extract can be effectivelyused in modified dosage form of deodorant Aerosol formulation. Materials& method: Ethanolicextracts of Ushira (1:3), sariva (1:1.6)and Bilva patra (1:1.8) drug : solvent respectively were obtainedthrough soxhlet extraction at Department of RSBK, IPGT & RA, Jamnagar. Extracts were mixed in theratio of 2:1:1 and were formulated to deodorant Aerosol form “SEVYA”. The mixture of extracts wassubjected to antimicrobial study at IIAPS, Gujarat Ayurveda University, Jamnagar by Paper disc diffusionmethod (Kirby-Bauer Method). Inoculate of S. aureus, S.epidermidis and Salmonella on nutrient agarwere incubated with discs soaked in test mixture at 37 0 C for 24 hours. Result:here was 10mm zone ofinhibition after 24 hrs. Conclusion: Mixture of ethanolic extracts of Ushira (), sariva and Bilva obtainedthrough soxhlet extraction in the ratio of 2:1:possesantimicrobial property against S.aureus, and S.epidermidis.

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