Dr. Sanjay Kumar Yadav, Prof. Dr. Navin Kumar Chaudhary, Dr. Anup Poudyal
Vol. 22, Issue 1, Jul-Dec 2026
Abstract:
Klebsiella pneumoniae is a Gram-negative bacterium that commonly colonizes the gastrointestinal tract. Carbapenems are β-lactam antibiotics used against multidrug-resistant pathogens. Carbapenemase-producing K. pneumoniae (CP-KP) has been on the rise since the 1990s. Resistance mechanisms include carbapenemase production and other modifications. Common carbapenemases in K. pneumoniae include KPC, NDM, and OXA-48. Molecular detection methods PCR, have specificity, and phenotypic methods can detect a broader range of carbapenemases, making them practical for clinical laboratories.
DOI: http://doi.org/10.37648/ijrmst.v22i01.002
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